Search Publications

by Ta L. D. H., Chan J. C. Y., Yap G. C., Purbojati R., Moses D.A., Koh Y. M. , Tay C. J. X., Huang C.-H., Kioh D. Y. Q., Woon J. Y., Tham E. H., Loo E. X. L., Shek L. P. C., Karnani N., Goh A., Van Bever H. P. S., Teoh O. H., Chan Y. H., Lay C., Knol J., Yap F., Tan K. H., Chong Y.-S., Godfrey K. M., Kjelleberg S., Schuster S.C., Chan E. C. Y., Lee B. W.

Reference: Gut Microbes (2020) 12: e1801964-1801962

Research Cluster(s): Biofilm Biology Meta-'omics & Microbiomes

Programme(s): Host Microbiome (Holobiont) Interactions Public Health & Medicine

Convection and the extracellular matrix dictate inter- and intra-biofilm quorum sensing communication in environmental systems

by Tan C.H., Oh H., Sheraton V. M., Mancini E., Loo J. S. C., Kjelleberg S., Sloot P. M. A., Rice S.A.

Reference: Environmental Science & Technology (2020) 54: 6730–6740

Research Cluster(s): Biofilm Biology

Response of microbial membranes to butanol: Interdigitation vs. disorder

by Guo J., Guo J., Ho J. C. S., Chin H., Mark A. E., Zhou C. , Kjelleberg S., Liedberg B., Parikh A. N., CHO Nam-Joon, Hinks J., Mu Y., Seviour T. W.

Reference: Physical Chemistry Chemical Physics (2020) 21: 11903-11915

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing

Longitudinal assessment of antibiotic resistance gene profiles in gut microbiomes of infants at risk of eczema

by Loo E. X. L., Zain A., Yap G. C., Purbojati R., Moses D.A., Koh Y. M. , Chong Y. S., Tan K. H., Gluckman P. D., Yap F., Eriksson J. G., Tham E., Shek L. P.-C., Kjelleberg S., Schuster S.C., Banerjee R., Lee B. W.

Reference: BMC Infectious Diseases (2020) 20: 312-312

Research Cluster(s): Meta-'omics & Microbiomes

Programme(s): Public Health & Medicine

Rapid microevolution of biofilm cells in response to antibiotics

by Penesyan A., Nagy S.S., Kjelleberg S., Gillings M.R., Paulsen I.T.

Reference: npj Biofilms and Microbiomes (2019) 5: 34.

Research Cluster(s): Biofilm Biology

Programme(s): Biofilm Detection and Control

Vibrio cholerae residing in food vacuoles expelled by protozoa are more infectious in vivo

by Espinoza-Vergara G., Noorian P., Silva-Valenzuela C. A., Raymond B. B. A., Allen C., Hoque M. M., Sun S., Johnson M. S., Pernice M., Kjelleberg S., , Djordjevic S. P., Labbate M., McDougald D.

Reference: Nature Microbiology (2020) 4: 2466–2474

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Public Health & Medicine

A chain-elongated oligophenylenevinylene electrolyte increases microbial membrane stability

by Zhou C., Chia W. N. G., Ho J. C. S., Moreland A. S., Seviour T. W., Liedberg B., Parikh A. N., Kjelleberg S., Hinks J., Bazan G. C.

Reference: Advanced Materials (2019) 31: e1808021

Research Cluster(s): Biofilm Biology Environmental Engineering

Interactions within the microbiome alter microbial interactions with host chemical defences and affect disease in a marine holobiont

by Longford S., Campbell A.H. , Nielsen S., Case R.J. , Kjelleberg S., Steinberg P. D.

Reference: Scientific Reports (2019) 9: 1363

Research Cluster(s): Biofilm Biology

Programme(s): Marine Biofilms & Microbiomes

Extracellular polymeric substances of biofilms: Suffering from an identity crisis

by Seviour T. W., Derlon N., Dueholm M.S., Flemming H.-C., Girbal-Neuhauser E., Horn H., Kjelleberg S., van Loosdrecht M.C.M., Lotti T., Malpei M.F., Nerenberg R., Neu T.R., Paul E., , Yu H.

Reference: Water Research (2019) 151: 1-7.

Research Cluster(s): Biofilm Biology Environmental Engineering

Programme(s): Bioprocessing

Matrix polysaccharides and SiaD diguanylate cyclase alter community structure and competitiveness of Pseudomonas aeruginosa during dual-species biofilm development with Staphylococcus aureus

by Chew S. C., Chew S.C., Yam K. H. J., Matysik A. S., Seng Z.J., , Givskov M., Givskov M., Rice S. A., Yang L., Kjelleberg S.

Reference: mBio (2018) 9: e00585-00518

Research Cluster(s): Biofilm Biology

Mixed community biofilms and microbially influenced corrosion

by Marsili E., Kjelleberg S., Rice S. A.

Reference: Microbiology Australia (2018) 39: 152-157.

Research Cluster(s): Biofilm Biology

Programme(s): Experimental Biofilms & Synthetic Ecology

Metagenomics approach to the human conjunctival microbiome

by Tong L., Hou A., Constancias F., Yang L., Kjelleberg S.

Reference: Investigative Ophthalmology & Visual Science (2018) 59: 3306-3306.

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions

Metagenomics reveals the influence of land use and rain on the benthic microbial communities in a tropical urban waterway

by Saxena G., Mitra S., Marzinelli E., Xie C., Wei T. J., Steinberg P. D., Williams R. B. H., Kjelleberg S., Lauro F. M., Swarup S.

Reference: mSystems (2018) 3: e00136-00117

Research Cluster(s): Environmental Engineering Meta-'omics & Microbiomes

Programme(s): Urban Water Cycle

Informed molecular design of conjugated oligoelectrolytes to increase cell affinity and antimicrobial activity

by Zhou C., Chia W. N. G., Ho J.C.S., Seviour T. W., Sailov T., Liedberg B., Kjelleberg S., Hinks J., Bazan G. C.

Reference: Angewandte Chemie International Edition (2018) 57: 8069-8072.

Research Cluster(s): Biofilm Biology Environmental Engineering

Programme(s): Biofilm Detection and Control

Functional biogeography and host specificity of bacterial communities associated with the marine green alga Ulva spp.

by Roth-Schulze A. J., Pintado J., Zozaya-Valdés E., Cremades J., Ruiz P., Kjelleberg S., Thomas T.

Reference: Molecular Ecology (2018) 27: 1952–1965

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Low-dose nitric oxide as targeted anti-biofilm adjunctive therapy to treat chronic Pseudomonas aeruginosa infection in cystic fibrosis

by Howlin R.P., Cathie K., Hall-Stoodley L., Cornelius V., Duignan C., Allan R.N., Fernandez B.O., Barraud N., Bruce K.D., Jefferies J., Kelso M., Kjelleberg S., Rice S. A., Rice S.A., , Rogers G.B., Pink S., Smith C., Sukhtankar P.S., Salib R., Legg J., Carroll M., Daniels T., Feelisch M., Stoodley P., Clarke S.C., Connett G.

Reference: Molecular Therapy (2017) 25: 2104-2116.

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing Host Microbiome (Holobiont) Interactions Biofilm Detection and Control

Mechanistic action of weak acid drugs on biofilms

by Kundukad B., Schussman M., Yang K., Seviour T. W., Yang L., Rice S. A., Kjelleberg S.

Reference: Scientific Reports (2017) 7: 4783

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing Biofilm Detection and Control

Enhancement of lipase stability and productivity through chemical modification and its application to latex-based polymer emulsions

by Jayawardena M.B., Yee L.H., Poljak A., Cavicchioli R., Kjelleberg S., Siddiqui K.

Reference: Process Biochemistry (2017) 57: 131-140

Research Cluster(s): Biofilm Biology

Cyclic-di-GMP is required for corneal infection by Pseudomonas aeruginosa and modulates host immunity

by Yam K. H. J., Aung T. T., Chua S. L., Chen Y., Kohli G.S., Zhou J., Constancias F., Liu Y., Cai Z., Salido S.S., Moses D., Rice S. A., Schuster S. C., Wu B., Kjelleberg S., Tolker-Nielsen T., Bueurman R. W., Givskov M., Yang L.

Reference: bioRxiv (2017): doi.org/10.1101/098749

Research Cluster(s): Biofilm Biology Meta-'omics & Microbiomes

Programme(s): Host Microbiome (Holobiont) Interactions Biofilm Detection and Control

Epigallocatechin gallate remodels overexpressed functional amyloids in Pseudomonas aeruginosa and increases biofilm susceptibility to antibiotic treatment

by Stenvang, Marcel, Dueholm, Seviour T. W., Vad, Brian S., , Zeng, Guanghong, Kjelleberg S., Nielsen P. H., Søndergaard

Reference: Journal of Biological Chemistry (2016) 291(51): 26540-26553

Research Cluster(s): Biofilm Biology Environmental Engineering

Real time, spatial and temporal mapping of the distribution of c-di-GMP during biofilm development

by H. Nair, Periasamy S., Yang L., Kjelleberg S., Rice S. A.

Reference: Journal of Biological Chemistry (2017) 292: 477-487

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing Developmental Biology of Biofilms

Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels

by Chua S. L., Ding Y., Liu Y., Cai Z., Swarup S., Moses D., Schuster S. C., Kjelleberg S., Givskov M., Yang L.

Reference: Open Biology (2016) 6(11) DOI: 10.1098/rsob.160162

Research Cluster(s): Biofilm Biology Environmental Engineering Meta-'omics & Microbiomes

Programme(s): Developmental Biology of Biofilms Biofilm Detection and Control

All together now: Experimental multispecies biofilm model systems

by Tan C.H., Lee K. W. K., Burmølle M., Kjelleberg S., Rice S. A.

Reference: Environmental Microbiology (2016) DOI: 10.1111/1462-2920.13594

Research Cluster(s): Biofilm Biology

Biofilms: An emergent form of bacterial life

by Flemming H.-C., Wingender J., Szewzyk U., Steinberg P. D., Rice S. A., Kjelleberg S.

Reference: Nature Reviews Microbiology (2016) 14: 563-575.

Research Cluster(s): Biofilm Biology

Programme(s): Experimental Biofilms & Synthetic Ecology Bioprocessing Developmental Biology of Biofilms Public Health & Medicine

Next-generation studies of microbial biofilm communities

by Rice S. A., Wuertz S., Kjelleberg S.

Reference: Microbial Biotechnology (2016) 9: 677-680

Research Cluster(s): Biofilm Biology Environmental Engineering

Programme(s): Experimental Biofilms & Synthetic Ecology

Multiple opportunistic pathogens can cause a bleaching disease in the red seaweed Delisea pulchra

by Kumar V., Zozaya-Valdes E., Kjelleberg S., Thomas T., Egan S.

Reference: Environmental Microbiology (2016) 18: 3962-3975

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Sex, scavengers, and chaperones: Transcriptome secrets of divergent symbiodinium thermal tolerances

by Levin R. A., Beltran V. H., Hill R., Kjelleberg S., McDougald D., Steinberg P. D., van Oppen M. J. H.

Reference: Molecular Biology and Evolution (2016) 33: 2201-2215

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Mechanical properties of the superficial biofilm layer determine the architecture of biofilms

by Doyle P.S., Seviour T. W., Kjelleberg S., Rice S. A., Kundukad B., Yang L.

Reference: Soft Matter (2016) 12: 5718-5726

Research Cluster(s): Biofilm Biology

Mechanical signatures of microbial biofilms in micropillar-embedded growth chambers

by Chew S.C., Kundukad B., Teh W. K. , Doyle P., Yang L., Rice S. A., Kjelleberg S.

Reference: Soft Matter (2016) 12: 5224-5232.

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing

SiaA/D interconnects c-di-GMP and RsmA signaling to coordinate cellular aggregation of Pseudomonas aeruginosa in response to environmental conditions

by Colley B., Dederer V., Carnell M., Kjelleberg S., Rice S. A., Klebensberger J.

Reference: Frontiers in Microbiology (2016) 7: Article 179

Research Cluster(s): Biofilm Biology

Programme(s): Developmental Biology of Biofilms

Effect of interspecific competition on trait variation in Phaeobacter inhibens biofilms

by Lutz C., Thomas T., Steinberg P. D., Kjelleberg S., Egan S.

Reference: Environmental Microbiology (2016) 18: 1635-1645

Research Cluster(s): Biofilm Biology

Programme(s): Experimental Biofilms & Synthetic Ecology

In situ mapping of the mechanical properties of biofilms by particle-tracking microrheology

by Chew S.C., Rice S. A., Kjelleberg S., Yang L.

Reference: Jove-Journal of Visualized Experiments 106: e53093.

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing

Enhancement in hydrogen evolution using Au-TiO2 hollow spheres with microbial devices modified with conjugated oligoelectrolytes

by Ngaw, Wang V. B., , Liu, Kjelleberg S., Zhang Q., Yi, Loo J. S. C.

Reference: npj Biofilms and Microbiomes (2015) 1: 15020

Research Cluster(s): Biofilm Biology Environmental Engineering

VarR controls colonization and virulence in the marine macroalgal pathogen Nautella Italica R11

by Gardiner M., Fernandes N., Nowakowski D., Raftery M., Kjelleberg S., Zhong L., Thomas T., Egan S.

Reference: Frontiers in Microbiology (2015) 6: 1130.

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Dispersal from microbial biofilms

by N. Barraud, Kjelleberg S., Rice S. A.

Reference: Barraud N., Kjelleberg S. and Rice S. A. (2015). Dispersal from microbial biofilms. In: M. Ghannoum, M. Parsek, M. Whiteley and P. Mukherjee (eds) Microbial Biofilms, 2nd Ed. Washington DC, ASM Press: pp. 343-362.

Research Cluster(s): Biofilm Biology

Increased microbial butanol tolerance by exogenous membrane insertion molecules

by Hinks J., Wang K., Matysik A. S., Kraut R., Kjelleberg S., Mu Y., Bazan G. C., Wuertz S., Seviour T. W.

Reference: ChemSusChem (2015) 8: 3718-3726.

Research Cluster(s): Biofilm Biology Environmental Engineering

Interspecific diversity reduces and functionally substitutes for intraspecific variation in biofilm communities

by Lee K. W. K., Yam K. H. J., Mukherjee M., Periasamy S., Steinberg P. D., Kjelleberg S., Rice S. A.

Reference: The ISME Journal (2016) 10: 846-857.

Research Cluster(s): Biofilm Biology

Pseudomonas aeruginosa PAO1 exopolysaccharides are important for mixed species biofilm community development and stress tolerance

by H. Nair, Lee K. W. K., Periasamy, , Rice S. A., Ong, Kjelleberg S.

Reference: Frontiers in Microbiology (2015) 6: Article 851.

Research Cluster(s): Biofilm Biology

Programme(s): Experimental Biofilms & Synthetic Ecology Bioprocessing

Chemically functionalized conjugated oligoelectrolyte nanoparticles for enhancement of current generation in microbial fuel cells

by Ding Y., Kjelleberg S., Wang V. B., Cao B., Wei Huang, Lianhui Wang, Biqing Bao, Zhang Q., Loo J. S. C., Cui-e Zhao, Jia Chen

Reference: ACS Applied Materials & Interfaces (2015) 7(26): 14501-14505

Research Cluster(s): Biofilm Biology Environmental Engineering

Metabolite-enabled mutualistic interaction between Shewanella oneidensis and Escherichia coli in a co-culture using an electrode as electron acceptor

by Wang V. B., Sivakumar K., Yang L., Zhang Q., Kjelleberg S., Loo J. S. C., Cao B.

Reference: Scientific Reports (2015) 5: 11222

Research Cluster(s): Biofilm Biology Environmental Engineering

Community quorum sensing signalling and quenching: microbial granular biofilm assembly

by Tan C.H., Koh K.S., Xie C., Zhang J., Tan X.H., Lee G.P., Zhou Y., Ng W.J., Rice S. A., Kjelleberg S.

Reference: npj Biofilms And Microbiomes (2015) 1

Research Cluster(s): Biofilm Biology

C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth

by Chua S. L., Sivakumar K., Morten Yuan, Yuan M., Jens Bo Nielsen, Nielsen T.E., Givskov M., Tim Cao, Cao B., Kjelleberg S., Yang L.

Reference: Scientific Reports (2015) 5: 10052.

Research Cluster(s): Biofilm Biology

Programme(s): Developmental Biology of Biofilms Biofilm Detection and Control

Pseudomonas aeruginosa PAO1 exopolysaccharides are important for mixed species biofilm community development and stress tolerance

by Periasamy S., H. Nair, Lee K. W. K., Ong J., Goh J.Q.J., Kjelleberg S., Rice S. A.

Reference: Frontiers in Microbiology (2015) 6: Article 851.

Research Cluster(s): Biofilm Biology

Programme(s): Experimental Biofilms & Synthetic Ecology

Ecogenomics reveals metals and land-use pressures on microbial communities in the waterways of a megacity

by Saxena G., Marzinelli E., Naing N.N., He Z., Yang L., Tom L., Mitra S., Ping H., Joshi U.M., Reuben S., Mynampati K.C., Mishra S., Umashankar S., Zhou J., Andersen G.L., Kjelleberg S., Swarup S.

Reference: Environmental Science & Technology (2015) 49(3): 1462-1471

Research Cluster(s): Environmental Engineering

Programme(s): Urban Water Cycle

Enhancing bidirectional electron transfer of Shewanella oneidensis by a synthetic flavin pathway

by Ding Y., Hao Song, Rice S. A., Cao B., Yidan Hu, Kjelleberg S., Yun Yang

Reference: ACS Synthetic Biology (2015) 4(7): 815-823.

Research Cluster(s): Biofilm Biology Environmental Engineering

Quorum sensing-regulated chitin metabolism provides grazing resistance to Vibrio cholerae biofilms

by Sun S., Tay Q. X. M., Kjelleberg S., Rice S. A., McDougald D.

Reference: The ISME Journal (2015) 9(8): 1812-1820

Research Cluster(s): Biofilm Biology

Voltammetric profiling of redox-active metabolites expressed by Pseudomonas aeruginosa for diagnostic purposes

by Seviour T. W., Doyle L. E., S.J.L. Lauw, Hinks J., Rice S. A., V.J.Nesatyy, R. D. Webster, Kjelleberg S., Marsili E.

Reference: Chemical Communications (2015) 51(18): 3789-3792

Research Cluster(s): Biofilm Biology Environmental Engineering

Functional amyloids keep quorum sensing molecules in check

by Seviour T. W., Hansen S.H., Liu Y., Yau Y.H., Wang V. B., Stenvang M.R., Christiansen G., Marsili E., Givskov M., Chen Y., Otzen D.E., Nielsen P. H., Shochat S.G., Kjelleberg S., Dueholm M.S.

Reference: Journal of Biological Chemistry (2015) 290(10): 6457-6469

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing

Solvent optimization for bacterial extracellular matrices: a solution for the insoluble

by Seviour T. W., Weerachanchai P., Hinks J., Roizman D., Rice S. A., Bai L., Lee J.-M., Kjelleberg S.

Reference: RSC Advances (2015) 5(10): 7469-7478

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing

The application of nitric oxide to control biofouling of membrane bioreactors

by Luo J., Zhang J., Barnes R.J., Tan X., McDougald D., Fane A.G., Zhuang G., Kjelleberg S., Cohen Y., Rice S. A.

Reference: Microbial Biotechnology (2015)

Research Cluster(s): Biofilm Biology

Analysis of microbial community composition in a lab-scale membrane distillation bioreactor

by Zhang Q., Shuwen G., Zhang J., Fane A.G., Kjelleberg S., Rice S. A., McDougald D.

Reference: Journal of Applied Microbiology (2015) 118: 940-953

Research Cluster(s): Biofilm Biology Environmental Engineering

Employing a flexible and low-cost polypyrrole nanotube membrane as an anode to enhance current generation in microbial fuel cells

by Zhao C.-e., Wu J., Kjelleberg S., Loo J. S. C., Zhang Q.

Reference: Small (2015) In press

Research Cluster(s): Environmental Engineering

Hybrid conducting biofilm with built-in bacteria for high-performance microbial fuel cells

by Zhao C.-e., Wu J., Ding Y., Wang V. B., Zhang Y., Kjelleberg S., Loo J. S. C., Cao B., Zhang Q.

Reference: ChemElectroChem (2015) 2(5): 654-658.

Research Cluster(s): Environmental Engineering

Nitric oxide treatment for the control of reverse osmosis membrane biofouling

by Barnes R.J., Hui L.J., Bandi R.R., Ru F.C.H, Tay Q. X. M., Aung T., Fane A.G., Kjelleberg S., Rice S. A.

Reference: Applied and Environmental Microbiology (2015) 81(7): 2515-2524

Research Cluster(s): Biofilm Biology

Programme(s): Urban Water Cycle Biofilm Detection and Control

Characterization of the archaeal community fouling a membrane bioreactor

by Luo J., Zhang J., Tan X., McDougald D., Zhuang G., Fane A.G., Kjelleberg S., Cohen Y., Rice S. A.

Reference: Journal of Environmental Sciences (2015) 29: 115-123

Research Cluster(s): Biofilm Biology

Environmental cues and genes involved in establishment of the superinfective Pf4 phage of Pseudomonas aeruginosa

by Hui J.G.K., Mai-Prochnow A., Kjelleberg S., McDougald D., Rice S. A.

Reference: Frontiers in Microbiology (2014) 5: Article 654

Research Cluster(s): Biofilm Biology

Programme(s): Experimental Biofilms & Synthetic Ecology

Aroyleneimidazophenazine: A sensitive probe for detecting CN- anion and its solvatochromism effect

by Zhao J., Li J., Li G., Gao J., Kjelleberg S., Loo J. S. C., Zhang Q.

Reference: Journal of Heterocyclic Chemistry (2014)

Research Cluster(s): Environmental Engineering

The correlation between biofilm biopolymer composition and membrane fouling in submerged membrane bioreactors

by Luo J., Zhang J., Tan X., McDougald D., Zhuang G., Fane A.G., Kjelleberg S., Cohen Y., Rice S. A.

Reference: Biofouling (2014) 30(9): 1093-1110

Research Cluster(s): Biofilm Biology

Nitric oxide: A key mediator of biofilm dispersal with applications in infectious diseases.

by Barraud N., Kelso M.J., Rice S. A., Kjelleberg S.

Reference: Current Pharmaceutical Design (2015) 21: 31-42

Research Cluster(s): Biofilm Biology

Dynamic remodeling of microbial biofilms by functionally distinct exopolysaccharides

by Chew S.C., Kundukad B., Seviour T. W., van der Maarel J.R.C., Liu Y., Rice S. A., Doyle P., Kjelleberg S.

Reference: mBio (2014) 5(4): e01536-01514

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing

Membrane permeabilization underlies the enhancement of extracellular bioactivity in Shewanella oneidensis by a membrane-spanning conjugated oligoelectrolyte

by Sivakumar K., Wang V. B., Chen X., Bazan G. C., Kjelleberg S., Loo J. S. C., Cao B.

Reference: Applied Microbiology and Biotechnology (2014) 98: 9021-9031

Research Cluster(s): Biofilm Biology

Microbial biofilm formation: A need to act

by Romling U., Kjelleberg S., Normark S., Nyman L., Uhlin B.E., Akerlund B.

Reference: Journal of Internal Medicine (2014) 276(2): 98-110

Research Cluster(s): Biofilm Biology

Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles

by Chua S. L., Liu Y., Yam K. H. J., Chen Y., Vejborg R.M., Tan B.G.C., Kjelleberg S., Tolker-Nielsen T., Givskov M., Yang L.

Reference: Nature Communications (2014) 5: 4462

Research Cluster(s): Biofilm Biology

Programme(s): Developmental Biology of Biofilms

Comparative genomic analysis of malaria mosquito vector-associated novel pathogen Elizabethkingia anophelis

by Teo J., Tan S.Y., Liu Y., Tay Q. X. M., Ding Y., Li Y., Kjelleberg S., Givskov M., Lin R.T.P., Yang L.

Reference: Genome Biology and Evolution (2014) 6(5): 1158-1165

Research Cluster(s): Biofilm Biology

Biofilm development and enhanced stress resistance of a model, mixed-species community biofilm

by Lee K. W. K., Periasamy S., Mukherjee M., Xie C., Kjelleberg S., Rice S. A.

Reference: The ISME Journal (2014) 8(4): 894-907

Research Cluster(s): Biofilm Biology

Comparison of flavins and a conjugated oligoelectrolyte in stimulating extracellular electron transport from Shewanella oneidensis MR-1

by Wang V. B., Kirchhofer N.D., Chen X., Tan M.Y.L., Sivakumar K., Cao B., Zhang Q., Kjelleberg S., Bazan G. C., Loo J. S. C., Marsili E.

Reference: Electrochemistry Communications (2014) 41(0): 55-58

Research Cluster(s): Biofilm Biology Environmental Engineering

Strain-specific parallel evolution drives short-term diversification during Pseudomonas aeruginosa biofilm formation

by McElroy K.E., Hui J.G.K., Woo J.K.K., Luk A.W.S, Web J.S., Kjelleberg S., Rice S. A., Thomas T.

Reference: Proceedings of the National Academy of Sciences USA (2014) 111 (14): E1419-E1427

Research Cluster(s): Biofilm Biology

Programme(s): Developmental Biology of Biofilms

Bacterial communication systems

by Harder T., Rice S. A., Dobretsov S., Thomas T., Steinberg P.D., Kjelleberg S., McDougald D.

Reference: Outstanding Marine Molecules and New Trends in Analytical Methods (2014)

Research Cluster(s): Biofilm Biology

Uncovering alternate charge transfer mechanisms in Escherichia coli chemically functionalized with conjugated oligoelectrolytes

by Wang V.B., Yantara N., Koh T.M., Kjelleberg S., Zhang Q., Bazan G. C., Loo J. S. C., Mathews N.

Reference: Chemical Communications (2014) 50(60): 8223-8226

Research Cluster(s): Biofilm Biology

Micro-fabricated polydimethyl siloxane (PDMS) surfaces regulate the development of marine microbial biofilm communities

by Ling G.C., Low M.H., Erken M., Longford S., Nielsen S., Poole A., Steinberg P., McDougald D., Kjelleberg S.

Reference: Biofouling (2014) 30(3): 323-335

Research Cluster(s): Biofilm Biology

Programme(s): Marine Biofilms & Microbiomes

Biogenic tellurium nanorods as a novel antivirulence agent inhibiting pyoverdine production in Pseudomonas aeruginosa

by Mohanty A., Kathawala M.H., Zhang J., Chen W.N., Loo J. S. C., Kjelleberg S., Yang L., Cao B.

Reference: Biotechnology and Bioengineering (2014) 111(5): 858–865

Research Cluster(s): Biofilm Biology

Programme(s): Biofilm Detection and Control

The roles of Pseudomonas aeruginosa extracellular polysaccharides in biofouling of reverse osmosis membranes and nitric oxide induced dispersal

by Barnes R.J., Bandi R.R., Ru F.C.H., Hui L.J., Aung T., Barraud N., Fane A.G., Kjelleberg S., Rice S. A.

Reference: Journal of Membrane Science (2014) 466: 161-172

Research Cluster(s): Biofilm Biology

Programme(s): Urban Water Cycle Biofilm Detection and Control

Larger pi-extended anti-/syn-aroylenediimidazole polyaromatic compounds: Synthesis, physical properties, self-assembly, and quasi-linear conjugation effect

by Zhao J., Wong J.I., Gao J., Li G., Xing G., Zhang H., Sum T.C., Yang H., Zhao Y., Kjelleberg S., Huang W., Loo J. S. C., Zhang Q.

Reference: RSC Advances (2014) 4 17822-17831

Research Cluster(s): Environmental Engineering

Modeling the membrane insertion of molecules designed for transmembrane electron transfer

by Hinks J., Wang Y., Poh W. H., Donose B.C., Thomas A.W., Wuertz S., Loo J. S. C., Bazan G. C., Kjelleberg S., Mu Y., Seviour T. W.

Reference: Langmuir (2014) 30(9): 2429–2440

Research Cluster(s): Biofilm Biology Environmental Engineering

The role of quorum sensing signalling in EPS production and the assembly of a sludge community into aerobic granules

by Tan C.H., Koh K.S., Xie C., Tay Q. X. M., Zhou Y., Williams R. B. H., Ng W.J., Rice S. A., Kjelleberg S.

Reference: The ISME Journal (2014) 8: 1186-1197

Research Cluster(s): Biofilm Biology Environmental Engineering Meta-'omics & Microbiomes

A stable synergistic microbial consortium for simultaneous azo dye removal and bioelectricity generation

by Wang V. B., Chua S. L., Cai Z., Sivakumar K., Zhang Q., Kjelleberg S., Cao B., Loo J. S. C., Yang L.

Reference: Bioresource Technology (2014) 155(0): 71-76

Research Cluster(s): Biofilm Biology

Characterization of biofouling in a lab-scale forward osmosis membrane bioreactor (FOMBR)

by Zhang Q., Jie Y.W., Loong W.L.C, Zhang J., Fane A.G., Kjelleberg S., Rice S. A., McDougald D.

Reference: Water Research (2014) 58(1): 141-151

Research Cluster(s): Biofilm Biology

Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database

by Tan S.Y., Chua S. L., Chen Y., Rice S. A., Kjelleberg S., Nielsen T.E., Yang L., Givskov M.

Reference: Antimicrobial Agents and Chemotherapy (2013) 57(11): 5629-5641

Research Cluster(s): Biofilm Biology

Programme(s): Biofilm Detection and Control

Bis-(3'-5')-cyclic dimeric GMP regulates antimicrobial peptide resistance in Pseudomonas aeruginosa

by Chua S. L., Tan S.Y., Rybtke M.T., Chen Y., Rice S. A., Kjelleberg S., Tolker-Nielsen T., Yang L., Givskov M.

Reference: Antimicrobial Agents and Chemotherapy (2013) 57(5): 2066-2075

Research Cluster(s): Biofilm Biology

Programme(s): Biofilm Detection and Control

The seaweed holobiont: Understanding seaweed-bacteria interactions

by Egan S., Harder T., Burke C., Steinberg P., Kjelleberg S., Thomas T.

Reference: FEMS Microbiology Reviews (2013) 37(3): 462-476

Research Cluster(s): Biofilm Biology

Molecular insights into environmental microbes

by Hennecke H., Kjelleberg S., Brussaard C.

Reference: FEMS Microbiology Reviews (2013) 37(3): 285-285

Research Cluster(s): Biofilm Biology Meta-'omics & Microbiomes

Engineering PQS biosynthesis pathway for enhancement of bioelectricity production in Pseudomonas aeruginosa microbial fuel cells

by Wang V. B., Chua S. L., Cao B., Seviour T. W., Nesatyy V.J., Marsili E., Kjelleberg S., Givskov M., Tolker-Nielsen T., Song H., Loo J. S. C., Yang L.

Reference: PLoS ONE (2013) 8(5): e63129

Research Cluster(s): Biofilm Biology Environmental Engineering

Dynamics of biofilm formation under different nutrient levels and the effect on biofouling of a reverse osmosis membrane system

by Chen X., Suwarno S.R., Chong T.H., McDougald D., Kjelleberg S., Cohen Y., Fane A.G., Rice S. A.

Reference: Biofouling (2013) 29(3): 319-330

Research Cluster(s): Biofilm Biology

Relative contributions of Vibrio polysaccharide and quorum sensing to the resistance of Vibrio cholerae to predation by heterotrophic protists

by Sun S.Y., Kjelleberg S., McDougald D.

Reference: PloS ONE (2013) 8(2): e56338

Research Cluster(s): Biofilm Biology

First case of E. anophelis outbreak in an intensive-care unit

by Teo J., Tan S.Y., Tay M., Ding Y., Kjelleberg S., Givskov M., Lin R.T.P., Yang L.

Reference: The Lancet (2013) 382(9895): 855-856

Research Cluster(s): Biofilm Biology

Assessing the effectiveness of functional genetic screens for the identification of bioactive metabolites

by Penesyan A., Ballestriero F., Daim M., Kjelleberg S., Thomas T., Egan S.

Reference: Marine Drugs (2013) 11(1): 40-49

Research Cluster(s): Biofilm Biology

Draft genome sequence of the chronic, nonclonal cystic fibrosis isolate Pseudomonas aeruginosa strain 18A

by Woo J.K.K., McElroy K., Rice S. A., Kirov S.M., Thomas T., Kjelleberg S.

Reference: Genome Announcements (2013) 1(2): e00001-00013

Research Cluster(s): Biofilm Biology

Influence of outer membrane c-type cytochromes on particle size and activity of extracellular nanoparticles produced by Shewanella oneidensis

by Ng C. K., Sivakumar K., Liu X., Madhaiyan M., Ji L., Yang L., Tang C., Song H., Kjelleberg S., Cao B.

Reference: Biotechnology and Bioengineering (2013) 110: 1831-1837

Research Cluster(s): Biofilm Biology Environmental Engineering

Optimal dosing regimen of nitric oxide donor compounds for the reduction of Pseudomonas aeruginosa biofilm and isolates from wastewater membranes

by Barnes R.J., Bandi R.R., Wong W.S., Barraud N., McDougald D., Fane A., Kjelleberg S., Rice S. A.

Reference: Biofouling (2013) 29(2): 203-212

Research Cluster(s): Biofilm Biology

Improving charge collection in Escherichia coli-carbon electrode devices with conjugated oligoelectrolytes

by Wang V. B., Du J., Chen X., Thomas A.W., Kirchhofer N.D., Garner L.E., Maw M.T., Poh W.H., Hinks J., Wuertz S., Kjelleberg S., Zhang Q., Loo J. S. C., Bazan G. C.

Reference: Physical Chemistry Chemical Physics (2013) 15(16): 5867-5872

Research Cluster(s): Biofilm Biology Environmental Engineering

Synthesis of cephalosporin-3'-diazeniumdiolates - a new class of biofilm dispersing NO-donor prodrugs activated by ß-lactamase

by Yepuri N.R., Barraud N., Kardak B.G., Kjelleberg S., Rice S. A., Kelso M.J.

Reference: Chemical Communications (2013) 49: 4791-4793

Research Cluster(s): Biofilm Biology

Programme(s): Biofilm Detection and Control

Draft genome sequence of Klebsiella pneumoniae strain KP-1

by Lee K. W. K., Arumugam K., Purbojati R., Tay Q. X. M., Williams R. B. H., Kjelleberg S., Rice S. A.

Reference: Genome Announcements (2013) 1(6): e01082-01013

Research Cluster(s): Biofilm Biology Meta-'omics & Microbiomes

Animals in a bacterial world, a new imperative for life sciences

by McFall-Ngai M.J., Hadfield M.G., Bosch T.C.G., Carey H.V., Domazet-Lo so T., Douglas A.E., Dubilier N., Eberl G., Fukami T., Gilbert S.F., Hentschel U., King N., Kjelleberg S., Knoll A.H., Kremer N., Mazmanian S.K., Metcalf J.L., Nealson K., Pierce N.E., Rawls J.F., Reid A., Ruby E.G., Rumpho M., Sanders J.G., Tautz D., Wernegreen J.J.

Reference: Proceedings of the National Academy of Sciences USA (2013) 110(9): 3229-3236

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions

Phaeobacter gallaeciensis genomes from globally opposite locations reveal high similarity of adaptation to surface life

by Thole S., Kalhoefer D., Voget S., Berger M., Engelhardt T., Liesegang H., Wollherr A., Kjelleberg S., Daniel R., Simon M., Thomas T., Brinkhoff T.

Reference: The ISME Journal (2012) 6: 2229-2244

The presence and role of bacterial quorum sensing in activated sludge

by Chong G., Kimyon O., Rice S. A., Kjelleberg S., Manefield M.

Reference: Microbial Biotechnology (2012) 5: 621-633.

Research Cluster(s): Biofilm Biology

Programme(s): Urban Water Cycle

Glucose starvation-induced dispersal of Pseudomonas aeruginosa biofilms is cAMP and energy dependent

by Huynh T.T., McDougald D., Klebensberger J., Budoor A.Q., Barraud N., Rice S. A., Kjelleberg S., Schleheck D.

Reference: PLoS ONE (2012) 7(8): e42874

Cephalosporin-3-diazeniumdiolates: Targeted NO-donor prodrugs for dispersing bacterial biofilms

by Barraud N., Kardak B.G., Yepuri N.R., Howlin R.P., Webb J.S., Faust S.N., Kjelleberg S., Rice S. A., Kelso M.J.

Reference: Angewandte Chemie (2012) 124: 9191-9194

Research Cluster(s): Biofilm Biology

Functional equivalence and evolutionary convergence in complex communities of microbial sponge symbionts

by Fan L., Reynolds D., Liu M., Stark M., Kjelleberg S., Webster N.S., Thomas T.

Reference: Proceedings of the National Academy of Sciences USA (2012) 109(27): E1878–E1887

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Biofilm shows spatially stratified metabolic responses to contaminant exposure

by Cao B., Majors P.D., Ahmed B., Renslow R.S., Silvia C.P., Shi L., Kjelleberg S., Fredrickson J.K., Beyenal H.

Reference: Environmental Microbiology (2012) 14(11): 2901-2910

Research Cluster(s): Biofilm Biology Environmental Engineering

Programme(s): Biofilm Detection and Control

Molecular dynamics unlocks atomic level self-assembly of the exopolysaccharide matrix of water-treatment granular biofilms

by Seviour T. W., Malde A.K., Kjelleberg S., Yuan Z., Mark A.E.

Reference: Biomacromolecules (2012) 13(6): 1965-1972

Research Cluster(s): Biofilm Biology

Programme(s): Bioprocessing Urban Water Cycle

Minimal increase in genetic diversity enhances predation resistance

by Koh K.S., Matz C., Tan C.H., Le H.L., Rice S. A., Marshall D.J., Steinberg P.D., Kjelleberg S.

Reference: Molecular Ecology (2012) 21(7): 1741-1753

Research Cluster(s): Biofilm Biology

Should we stay or should we go: Mechanisms and ecological consequences for biofilm dispersal

by McDougald D., Rice S. A., Barraud N., Steinberg P.D., Kjelleberg S.

Reference: Nature Reviews Microbiology (2012) 10(1): 39-50

Research Cluster(s): Biofilm Biology

Biofilm dispersal cells of a cystic fibrosis Pseudomonas aeruginosa isolate exhibit variability in functional traits likely to contribute to persistent infection

by Woo J.K.K., Webb J.S., Kirov S., Kjelleberg S., Rice S. A.

Reference: FEMS Immunology and Medical Microbiology (2012) 66(2): 251-264

Research Cluster(s): Biofilm Biology

Metaproteogenomic analysis of a community of sponge symbionts

by Liu M., Fan L., Zhong L., Kjelleberg S., Thomas T.

Reference: The ISME Journal (2012) 6(8): 1515-1525

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions

Dynamic modelling of cell death during biofilm development

by Fagerlind M.G., Webb J.S., Barraud N., McDougald D., Jansson A., Nilsson P., Harlén M., Kjelleberg S., Rice S. A.

Reference: Journal of Theoretical Biology (2012) 295(0): 23-36

Research Cluster(s): Biofilm Biology

Programme(s): Developmental Biology of Biofilms

Community structure and functional gene profile of bacteria on healthy and diseased thalli of the red seaweed Delisea pulchra

by Fernandes N., Steinberg P., Rusch D., Kjelleberg S., Thomas T.

Reference: PLoS ONE (2012) 7(12)

Genomes and virulence factors of novel bacterial pathogens causing bleaching disease in the marine red alga Delisea pulchra

by Fernandes N., Case R., Longford S., Seyedsayamdost M.R., Steinberg P. D., Kjelleberg S., Thomas T.

Reference: PLoS ONE (2011) 6: e27387.

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Bacterial community assembly based on functional genes rather than species

by Burke C., Steinberg P. D., Rusch D., Kjelleberg S., Thomas T.

Reference: Proceedings of the National Academy of Sciences USA (2011) 108: 14288-14293.

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Antidiatom and antibacterial activity of epiphytic bacteria isolated from Ulva lactuca in tropical waters

by Kumar V., Rao D., Thomas T., Kjelleberg S., Egan S.

Reference: World Journal of Microbiology and Biotechnology (2011) 27: 1543-1549.

Research Cluster(s): Biofilm Biology

Programme(s): Marine Biofilms & Microbiomes

Climate change and disease: Bleaching of a chemically defended seaweed

by Campbell A.H., Harder T., Nielsen S., Kjelleberg S., Steinberg P. D.

Reference: Global Change Biology (2011) 17: 2958-2970.

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Marine Biofilms & Microbiomes

Novel antibacterial proteins from the microbial communities associated with the sponge Cymbastela concentrica and the green alga Ulva australis

by Yung P. Y. M., Burke C., Lewis M., Kjelleberg S., Thomas T.

Reference: Applied and Environmental Microbiology 77: 1512-1515

Research Cluster(s): Biofilm Biology

Programme(s): Host Microbiome (Holobiont) Interactions Biofilm Detection and Control