A/Prof LOO Say Chye Joachim
Environmental Engineering cluster, SCELSE
School of Materials Science & Engineering, NTU

Research Interests

Delivery systems for biomedical and food-related applications, including encapsulation of probiotics and prebiotics for gut microbial community; Targeting of antimicrobials with lipid-polymer hybrid nanoparticles against intracellular pathogens and opportunistic biofilms.

Visiting Scientist, Harvard University, USA
Co-convenor, ISO/TC 229 WG3 Nanotechnology – Health and Safety
Committee Member, ISO/TC 229 Nanotechnology National Working Group
Member, American Nano Society
Member, Materials Research Society of Singapore (MRS-S) 

SCELSE publications


*For full publication and other details, please refer to: http://www.ntu.edu.sg/home/joachimloo/


  1. SCJ Loo, JS Baek, CH Tan. Lipid-polymer hybrid nanoparticles for localized and sustained delivery of antimicrobials. PCT/SG2019/050009. Jan 2019.
  2. P Demokritou, G Deloid, KW Ng, SCJ Loo. Methods for Reducing Bioavailability and Absorption of Ingested Substances. PCT/US18/60096. Sep 2018.
  3. P Demokritou, G Deloid, KW Ng, SCJ Loo. Carbohydrate digestion reduction by nanocellulose. US Provisional Patent 62/697,827. Jul 2018.
  4. SCJ Loo, JS Baek. Floatable pharmaceutical microcapsule composition. PCT/SG2018/050394. Aug 2018. Chinese Application No. : 201880048666.0. US Application No. : 16/635,310.
  5. HW Hou, BO Boehm, HM Tay, SCJ Loo. Leukocyte and microparticles fractionation using microfluidics. PCT Application: PCT/SG2016/050306. 30 June 2016. Japan Application No. : 2017-567746; US Application No. : 15/741,149. Dec 2017.
  6. SCJ Loo, JYG Lim. Feeding tubes integrated with responsive open circuits (ROC). Singapore provisional patent application number 10201602541Y. Mar 2016.
  7. SCJ Loo, S Kharel, WL Lee. Method of preparing hollow microparticles and hollow microparticles prepared thereof. PAT/223/14/14/SG PRVPCT/SG2015/050483. Dec 2015.
  8. J Hinks, JYE Han, SCJ Loo, S Wuertz. Electrochemical detection of E. coli. PCT/SG2015/050274. Aug 2015. Singapore Patent Application No: 11201700274X. US patent: 15/505,847. Dec 2018.
  9. SCJ Loo, WL Lee, PX Wee. Floating capsules encapsulating particles loaded with one or more drugs. PCT/SG2013/000282. National Phase: Singapore (11201500227S: Jan 2015) and USA. Granted: USA Patent No. 9,381,163 (Jul 2016). Singapore Patent Application No: 11201500227S (Nov 2016).
  10. SCJ Loo, MP Lim, WL Lee. Methods of manufacturing core-shell microparticles, and microparticles formed thereof. PCT/SG2013/000051. Granted: Singapore Application No. 11201404038P. (Mar 2015)
  11. T Steele, SCJ Loo, S Venkatraman, FYC Boey. A device for controlled release of a bioactive agent. PCT/SG2011/000457. US Application No. : 13/977,332. Jun 2013. Granted US Patent No. 9,801,831 (Mar 2018).
  12. T Steele, SCJ Loo, S Venkatraman, FYC Boey. Drug loaded nanoparticles and microparticles encapsulated into low-melting polyester wax films locally delivered by angioplasty balloons. PCT/SG2011/000457. Jun 2011.
  13. SCJ Loo, K Bastari, S Venkatraman. Method for coating particles with calcium phosphate and particles, microparticles and nanoparticles formed thereof. PCT/SG2011/000414. National phase: USA (Appl. No.: 13/885,931), Europe (Appl. No.: 11842961.2), Singapore.
  14. SCJ Loo, YL Khung, WL Lee. Method for encapsulating particles. PCT/SG2011/000414. National phase: Europe (Appl. No.: 11 842 853.1), Singapore (Appl. No.: 201303178-6). Granted: Singapore Patent No. 190009; USA Patent No. 9,616,031 B2 (Apr 2017)
  15. SCJ Loo, WL Lee. Multi-phase microparticles and method of manufacturing multi-phase microparticles. PCT/SG2010/000215. National phase: USA, China (ZL 2010 80034273.8). Granted: European Patent No. 2437879. (Jul 2017).
  16. S Venkatraman, SCJ Loo. Targeted drug delivery to bone. PCT/SG2010/000214. National phase: Singapore, China, Europe, India and USA (No. 13/375,713). Granted. USA Patent No. 8,933,058 (Jan 2015).