Research
SCELSE Imaging Facility

SCELSE has a strong long-term collaboration with several international manufacturers of imaging platforms for the development and application of new technologies for real-time imaging of defined mixed-species and complex environmental biofilms, and microbiomes hosted in higher organisms, in robust reproducible experimental settings.

 

The SCELSE Advanced Biofilm Imaging Facility provides state-of-the-art instrumentation tailored to meet the highly specialised and continually evolving needs of this newly emerging interdisciplinary ELSE research into controlling and harnessing biofilms. 
The facility’s instrumentation includes:

  • Zeiss Super Resolution System ELYRA PS.1with LSM 780 system
  • LSM 780 with 34 channels (32-GaAsP array detector + 2x PMTs)
  • Axio Observer Z1-Inverted epifluorescent microscope  
  • Axio Imager M2-Upright epifluorescent microscope 
  • Stereomicroscope "SteREO Discovery.V8"

The ELYRA PS.1 (Palm-Structured Illumination) Superresolution Microscope LSM 780 is the latest addition to the SCELSE Advanced Imaging Facility, joining the existing confocal microscope LSM 780. 

 

The LSM 780 has an illumination and detection system allows simultaneous acquisition of up to ten dyes resulting in images of extreme detail, even from the most difficult specimens. 

When coupled with the ELYRA PS.1, the LSM 780 systems provides a much higher resolution for all its images, localizing small structures and even single molecules, achieving effective lateral resolutions down to 20 nm.

SCELSE is part of the Singapore Light Microscopy Facilities Network (SLMFN) which fosters interaction between the different microscope facilities in Singapore by providing a regular forum for staff to meet and network. Established by Dr. Graham Wright (IMB, A*STAR) the network is now coordinated by a committee. Meetings take place every 2 months at different venues across the island and are supported by host institutes and microscopy companies.

Please click HERE to go to the SLMFN website.