Education & Training
PhD Research Projects

SCELSE creates opportunities for interactive and multi-disciplinary research by combining both emerging and core scientific disciplines such as but not limited to the following: microbiology and microbial ecology, biomedical sciences, chemistry, bioinformatics, genomics, civil and environmental engineering, materials science, microfluids, bioimaging, biophysics, computational and systems biology.

Research conducted by graduate students at molecular, cellular, community and process levels, will explore, understand and manage biofilm-driven processes. Advances in the ecology of microbial biofilm communities resulting from these projects will help deliver novel solutions to address complex problems applicable in a range of industrial, environmental and medical settings.

Click here for the list of available projects in SCELSE

You may also contact any of our researchers to discuss projects within the topics below, which can be custom designed to meet students’ research interests and the centre’s needs.

Environmental Engineering
  • Effect of physiochemical and operational parameters on structure and activity of microbial communities in water treatment systems
  • Novel applications of microbial communities in S, N and P cycles
  • Fate and transport of pathogens in surface waters
  • Enhanced electroconductivity of complex microbial communities for effective bioremediation of environmental pollutants
  • Resilience of microbial biofilm communities for river ecosystem function
  • Functional dynamics and modeling of biofilms in used water treatment
Meta-omics & Systems Biology
  • Systems biology of highly diverse microbial communities in the urban water cycle
  • Meta-transcriptomics of microbial communities in environmental engineered bioprocess systems
  • Metabolomics of environmental biofilm communities
  • Next generation sequencing of microbial biofilms
  • Temporal and spatial variation of airborne microbial communities (Dr Akira Uchida: AUchida@ntu.edu.sg)
  • Air-sea exchange of microbial communities (Dr James Houghton: jhoughton@ntu.edu.sg)
  • Adaptive response of airborne microbes (Dr Akira Uchida: AUchida@ntu.edu.sg)
  • Airborne microorganisms in key indoor environments in a tropical city (child-care centres, offices) (Dr Akira Uchida: AUchida@ntu.edu.sg)
  • Indoor airborne microbiome impact on human health
  • Source and sink of the outdoor air microbiome and its impact on the indoor air quality
  • Developing culturing methods for airborne microbes (Dr James Houghton: jhoughton@ntu.edu.sg)
Microbial Biofilms
  • Composition and the function of the extracellular matrix of bacterial biofilms (Dr Thomas Seviour: TWSeviour@ntu.edu.sg)
  • Understanding the biofilm life cycle using defined mixed species experimental systems
  • High resolution sensing and imaging to explore gradients and signaling in microbial biofilm communities
  • Role of phage and predators in shaping and controlling complex biofilm communities
  • Use of electro-analytics to quantify biofilm metabolites and extracellular electron transfer (Prof Cao Bin: BinCao@ntu.edu.sg or Dr Jamie Hinks: JHinks@ntu.edu.sg)
Public Health & Medical Biofilms
  • Chemical Biology for developing environmentally friendly biofilm control agents
  • Novel in vivo models for prevention and dispersal of pathogenic biofilms
  • Mechanism of resilience against stress and predation by the biofilm shield
  • Concealed and resistant microbial pathogens in the environment