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NTU-SCELSE team advances biosurveillance research

New research will establish a Singapore baseline for wildlife–human environmental interactions

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‘Good’ bacteria could boost coral resilience to heat stress

SCELSE researchers have identified a naturally occurring probiotic bacterium from the Roseobacteraceae family that could help corals withstand heat stress. The discovery was made by SCELSE PI and NTU School of Biological Sciences A/Prof Rebecca Case and SCELSE Research Fellow Dr Joao Pereyra, in collaboration with the St. John’s Island National Marine Laboratory (SJINML).

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SCELSE Principal Investigator Prof Joachim Loo appointed NTU Associate Vice Provost (Admissions), effective 1 Jul 2026

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SCELSE Research Director, Prof Alain Filloux Awarded Prestigious President's Chair in Molecular Microbiology

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Who we are

SCELSE (pronounced “cell-see”) is an interdisciplinary biofilm and microbiome research centre and a University Research Institute of Singapore’s Nanyang Technological University and National University of Singapore.

SCELSE studies microbial communities — including biofilms and microbiomes — to understand how microbes influence human health, industry, urban systems, and the environment. Through cutting-edge research, interdisciplinary collaboration, and global industry engagement, SCELSE develops sustainable solutions and real-world applications to address global challenges such as climate change, infectious diseases, resource resilience, and healthy ageing.

SCELSE’s research drives innovation in:

  • Public health and healthy ageing
  • Environmental sustainability and the circular bioeconomy
  • Industry and engineering applications
  • Food resilience and water systems
  • Societal and future resilience
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SCELSE’s Research Structure

Mission: “To discover, control and direct the behaviour of microbial biofilm communities and microbiomes for sustainable environmental, engineering, public health and medical applications.”

Environmental Engineering Cluster

Research in Environmental Engineering focuses on microbiomes in the urban water cycle, pollutant degradation, wastewater, nutrient removal, resource recovery and technologies for a circular bioeconomy.

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Biofilm Biology Cluster

SCELSE uses a multidisciplinary approach to understand the fundamental aspects of biofilm structure and function, studying how microbial interactions and the extracellular polymeric matrix impart the emergent properties that enable biofilm success.

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Meta-‘omics & Microbiomes Cluster

The Meta-'omics & Microbiomes cluster uses a top-down approach to identify microbiome and biofilm members, their functions, and community responses to novel and changing environments.

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Biofilms & Health Cluster

The Biofilms & Health cluster addresses public health and medical issues, focusing on prevention and treatment of biofilm infections and the development of sustainable antimicrobial technologies.

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Integrative Analysis Unit

The Integrative Analysis Unit addresses the need to comprehend the complexity of downstream analysis of metagenome and metatranscriptome datasets, ensure robust experimental design, to maximise data utilisation, and research output.

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